The synthesis of new potential photosensitizers. 1. Mono-carboxylic acid derivatives of tetraphenylporphyrin

نویسندگان

  • Grzegorz Zięba
  • Marcin Rojkiewicz
  • Violetta Kozik
  • Krystyna Jarzembek
  • Anna Jarczyk
  • Aleksander Sochanik
  • Piotr Kuś
چکیده

ABSTRACT A series of mono-alkylcarboxylic acid derivatives of tetraphenylporphyrin have been prepared. All the porphyrins were completely characterized by use of mass, 1H NMR, UV-visible, and fluorescence spectroscopy. Experimental log P were determined by use of reversed-phase thin-layer chromatography with use of log PRekker. These porphyrins are potential photosensitizers in photodynamic therapy. GRAPHICAL ABSTRACT .

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عنوان ژورنال:

دوره 143  شماره 

صفحات  -

تاریخ انتشار 2012